28 E. Coli (Carbapenem Resistant)
CDC Carbapenem-resistant Enterobacterales page
28.1 Epidemiologic Review
28.1.1 Disease Information
Overview: Carbapenem-resistant E. coli is a bacterium that is resistant to one or more carbapenem antibiotics. Carbapenemase-producing bacteria make enzymes called carbapenemases that inactivate carbapenems and other β-lactam antibiotics, including penicillins and cephalosporins. The five most common carbapenemases are KPC, NDM, VIM, OXA, and IMP.
Symptoms: Symptoms vary depending on the type of disease and some people may be asymptomatic.
Transmission: Person-to-person contact of infected stool or wounds. Contaminated medical equipment can also transmit disease.
Treatment: Treatment varies with each isolate. Some cases may be susceptible to a small number of antibiotics while others are pan-resistant, meaning no treatment is available.
Prevention Proper hand hygiene, use of personal protective equipment and environmental cleaning practices help reduce the spread of disease. Practicing antibiotic stewardship could help in reducing antibiotic resistance.
28.1.4 Monthly and Historical Comparisons
Data for Utah and the CDC were retrieved from the CDC’s Notifiable Infectious Disease Data Tables. National and state data was not available from the CDC for this disease in the time range at time of report.